Graduate Seminar with Joe Boldrey: Investigating the Influence Pulsed Magnetic Fields on Dopaminergic Neuronal Cells in Vitro


March 28, 2023    
2:10 pm - 3:00 pm


353 Durham Hall
Durham Hall, Ames

Event Type



Title: Investigating the influence pulsed magnetic fields on dopaminergic neuronal cells in vitro.

Abstract: Transcranial Magnetic Stimulation (TMS) is a non-invasive neuromodulation technique that is growing in acceptance by the medical community and the general public. TMS was approved by the U.S. Food and Drug Administration (FDA) for treating major depressive disorder (MDD) in 2008, certain types of migraine headaches in 2013, and obsessive-compulsive disorder (OCD) in 2018. Researchers are also investigating how TMS can be used for enhancing the recovery of motor functions after a stroke as well as other debilitating illnesses. Investigating the biological mechanisms involved in the brain’s response to TMS is a growing area of study. Of the many challenges that TMS researchers and clinicians face, are the ethical and safety standards that prevent the testing of new TMS devices and stimulation protocols on human subjects. To overcome these challenges, researchers use biological models such as animal subjects and neuronal cell lines developed from animals that recreate the aspects of cells in the human brain. In this talk, I will discuss the experimental results using two types of biological models to investigate, at the cellular level, the effects of magnetic fields generated by a commercial TMS system on neuronal cells in vitro.

Bio: Joe received his BS and MS degrees in Electrical Engineering from Iowa State University. During his undergraduate studies, his research covered a variety of areas including bioinformatics, magnetostriction in thin films, Barkhausen noise for nondestructive evaluation, and image processing for object detection. Currently, he is working on his PhD in electromagnets for biomedical applications.

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